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| Julius
P. A. Dewald, PT, PhD |
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| j-dewald@northwestern.edu |
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Bachelor of Science in Physical Therapy and Rehabilitation
Medicine
Vrije Universiteit Brussel, Brussels, Belgium, 1978
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Master of Science in Neurophysiology and Rehabilitation
Medicine
Vrije Universiteit Brussel, Brussels, Belgium, 1980 |
Doctor of Philosophy in Neurophysiology
Loma Linda University, Loma Linda, California, 1992 |
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Research in this lab is focused on understanding
discoordination of the upper limb after stroke, in learning
the involvement of brain plasticity in recovery, and
in developing novel neurotherapeutic training programs
to enhance motor control of the upper limb even years
after a stroke.
Using multi-channel EMG and a 6 degree-of-freedom load
cell, we can quantify discoordination in the impaired
arm and begin to investigate the mechanisms underlying
this reduction in muscle and torque combinations between
the elbow and shoulder joints. One main objective is
in understanding the relationship between the reduction
in movement capabilities and brain reorganization. Determination
of the nature of reorganization of motor cortices during
controlled mechanical experiments in hemiparetic stroke
subjects is expected to answer fundamental questions
regarding brain plasticity and its effects on motor
recovery.
Additional research interests involve the development
of novel neurotherapeutic training programs using quantitative
computer driven feedback that seek to improve the ability
to produce necessary muscle and torque combinations
for reaching and retrieval motions with the impaired
arm. I am also planning some future work on pharmacological
interventions that seek to alter spinal interneuronal
bias. Abnormal interneuronal excitability is believed
to be the source of altered spinal reflex activity following
brain lesions and may very well be an important contributor
to movement discoordination.
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2001 Nominated ‘Profesor Extraordinario’
de la Universidad San Sebastian, Concepcion, Chile,
for excellence in combining rehabilitation sciences
with quantitative biomedical engineering techniques.
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2000 RIC Women’s Board Award Direct Cost (DC)
$25,000 |
1997 RIC Women’s Board Award (DC) $35,000 |
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Peer
Reviewed Journal Articles (selected) |
-- Sukal TM, Ellis MD, Dewald JPA. Shoulder
Abduction-Induced Reductions in Reaching Work Area Following
Hemiparetic Stroke: Neuroscientific Implications.
Exp Brain Res. |
-- Beer RF, Ellis MD, Holubar BG, Dewald JP. Impact
of gravity loading on post-stroke reaching and its relationship
to weakness. Muscle Nerve. 2007 Aug;36(2):242-50.
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-- Krainak DM, Parrish TB, Dewald JP. A
method to capture six-degrees-of-freedom mechanical
measurements of isometric shoulder and elbow torques
during event-related fMRI. J Neurosci Methods.
2007 Apr 15;161(2):314-22. |
-- Ellis MD, Acosta AM, Yao J, Dewald JP. Position-dependent
torque coupling and associated muscle activation in
the hemiparetic upper extremity. Exp Brain Res.
2007 Feb;176(4):594-602. |
-- Yao J, Acosta AM, Dewald J. A
biomechanics-based method for the quantification of
muscle selectivity in a musculoskeletal system.
J Biomech. 2006;39(8):1527-30. Epub 2005 Jun
15. |
-- Ellis, M., Holubar, B., Acosta, A., Beer, R.,
& Dewald, J. Modifiability
of Abnormal Isometric Elbow and Shoulder Joint Torque
Coupling After Stroke. Muscle & Nerve.
2005 Aug;32(2): 170-8. |
-- Keller T, Ellis MD, Dewald JP. Overcoming
abnormal joint torque patterns in paretic upper extremities
using triceps stimulation. Artif Organs.
2005 Mar; 29(3):229-32. |
-- Deng J, Yao J, and Dewald J. Classification
of the intention to generate a shoulder versus elbow
torque by means of a time-frequency synthesized spatial
patterns BCI algorithm. J Neural Eng. 2005
Dec;2(4):131-8. Epub 2005 Oct 25. |
-- Yao J, Dewald J. Evaluation
of different cortical source localization methods using
simulated and experimental EEG data. Neuroimage.
2005 Apr 1;25(2):369-82. |
-- Lowery MM, Stoykov NS, Dewald JPA, and Kuiken
TA. Volume conduction in an anatomically-based surface
EMG model. IEEE Trans Biomed Eng 51(12): 2138-47, 2004 |
-- Beer RF, Dewald JP, Dawson ML, Rymer WZ. Target-dependent
differences between free and constrained arm movements
in chronic hemiparesis. Exp Brain Res.
2004 Jun;156(4):458-70. |
-- Ricamato AL, Dhaher YY, Dewald JP. Estimation
of active cortical current source regions using a vector
representation scanning approach. J Clin Neurophysiol.
2003 Sep-Oct;20(5):326-44. |
-- Koo TK, Mak AF, Hung L, Dewald JP. Joint
position dependence of weakness during maximum isometric
voluntary contractions in subjects with hemiparesis.
Arch Phys Med Rehabil. 2003 Sep;84(9):1380-6.
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-- Burgess PR, Jones LF, Buhler CF, Dewald JP, Zhang
LQ, Rymer WZ. Muscular
torque generation during imposed joint rotation: torque-angle
relationships when subjects' only goal is to make a
constant effort. Somatosens Mot Res. 2002;19(4):327-40.
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-- Dewald, JPA, Beer, RF. Abnormal
joint torque patterns in the paretic upper limb of subjects
with hemiparesis. Muscle & Nerve 24
(2): 273-283, 2001. |
-- Dewald, JPA, Sheshadri, V, Dawson, ML, Beer, RF.
Upper
limb discoordination in hemiparetic stroke: Implications
for neurorehabilitation. Topics in Stroke Rehabilitation
8(1) 1-12, 2001. |
-- Beer RF, Dewald JPA and Rymer WZ. Deficits
in the coordination of multijoint arm movements in hemiparetic
subjects. Evidence for disturbed control of limb dynamics.
Experimental Brain Research 131 (3): 305-319,
2000. |
-- Schmit BD, Dewald JP, Rymer WZ. Stretch
reflex adaptation in elbow flexors during repeated passive
movements in unilateral brain-injured patients.
Arch Phys Med Rehabil. 2000. Mar;81(3):269-78.
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-- Dewald, JPA, Beer, RF, Given JD, McGuire, J.R.,
and Rymer, WZ. Reorganization
of flexion reflexes in the upper extremity of hemiparetic
subjects. Muscle Nerve. 1999 Sep;22(9):1209-21.
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-- Beer, R.F, Dewald, J.P.A, Rymer, WZ. Disturbances
of Voluntary Movement in Stroke: Problems of Planning
or Execution? Progress in Brain Research
123: 455-60, 1999. |
-- Beer, RF, Given, JD, Dewald, JPA. Task-dependent
weakness at the elbow in patients with hemiparesis.
Arch Phys Med Rehabil. 1999 Jul;80(7):766-72.
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-- Schmit BD, Dhaher Y, Dewald JP, Rymer WZ. Reflex
torque response to movement of the spastic elbow: theoretical
analyses and implications for quantification of spasticity.
Ann Biomed Eng. 1999 Nov-Dec;27(6):815-29.
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-- Reinkensmeyer DJ, Dewald JP, Rymer WZ. Guidance-based
quantification of arm impairment following brain injury:
a pilot study. IEEE Trans Rehabil Eng.
1999 Mar;7(1):1-11. |
-- Reinkensmeyer DJ, Dewald JPA, and Rymer WZ. Robotic
devices for physical rehabilitation of stroke patients:
fundamental requirements, target therapeutic techniques,
and preliminary work, Technology and Disability. 5:
205-215, 1996. |
-- Dewald JP, Given JD, Rymer WZ. Long-lasting
reductions of spasticity induced by skin electrical
stimulation. IEEE Trans Rehabil Eng. 1996
Dec;4(4):231-42. Review. |
-- Given JD, Dewald JP, Rymer WZ. Joint
dependent passive stiffness in paretic and contralateral
limbs of spastic patients with hemiparetic stroke.
J Neurol Neurosurg Psychiatry. 1995 Sep;59(3):271-9.
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-- Dewald JP, Pope PS, Given JD, Buchanan TS, Rymer
WZ. Abnormal
muscle coactivation patterns during isometric torque
generation at the elbow and shoulder in hemiparetic
subjects. Brain. 1995 Apr;118 ( Pt 2):495-510.
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-- Dewald JPA and Given JD. Electrical Stimulation
and Spasticity Reduction: Fact or Fiction. Physical
Medicine & Rehabilitation: State of the Art Reviews.
8: 507-522, 1994. |
-- Buchanan TS, Moniz MJ, Dewald JP, Zev Rymer W.
Estimation
of muscle forces about the wrist joint during isometric
tasks using an EMG coefficient method. J Biomech.
1993 Apr-May;26(4-5):547-60. |
-- Leduc A, Lievens P, and Dewald JPA. The influence
of multidirectional vibrations on wound healing and
on regeneration of blood- and lymph vessels. Lymphology
14(4): 179-85, 1981.
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Book
Chapters |
-- Katz RT, Dewald JPA, and Schmit BD. Spasticity.
In: Physical Medicine & Rehabilitation, 2nd edition,
edited by Braddon RL. Philadelphia, PA: W.B. Saunders
Company, 2000.
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-- Rymer WZ, Dewald JPA, Given JD, and Beer RF. Abnormal
synergies in hemiparetic stroke: origins and implications
for movement control. In: Progress in Motor Control:
Bernstein's Traditions in Movement Studies, edited by
Latash ML. Champaign, IL: Human Kinetics, 1998. |
-- Dewald JPA and Rymer WZ. Factors underlying posture
and movement in spastic hemiparesis. In: Spasticity:
mechanisms and measurement, edited by Thilman A, Burke
D, and Rymer WZ. Stuttgart-New York: Springer Verlag.
p. 123-138, 1993. |
-- Dewald JPA. Sensorimotor neurophysiology and the
basis for neurofacilitation therapeutic techniques.
In: Stroke rehabilitation, edited by Brandstater ME
and Basmajian JV. Baltimore-London-Los Angeles-Sydney:
Williams & Wilkins, p. 109-182, 1987. |
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